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Agenerase

This page contains recent news articles, when available, and an overview of Agenerase but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Why is Agenerase prescribed? [MedMaster Patient Drug Information database]

Amprenavir is used in combination with other antiretroviral medications to treat human immunodeficiency virus (HIV). Amprenavir belongs to a class of drugs called protease (pro' tee ace) inhibitors, which slow the spread of HIV infection in the body.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Recent news articles mentioning Agenerase

Be cautious when taking St. John's wort with other drugs  -  Feb 6, 2007
Fort Wayne News Sentinel, ...nefazodone (Serzone); Antifungals (ketoconazole, itraconazole); Anti-HIV drugs, including protease inhibitors such as amprenavir, indinavir, nelfinavir,

How should Agenerase be used? [MedMaster Patient Drug Information database]

Amprenavir comes as a capsule and liquid to take by mouth. It is usually taken twice a day. Amprenavir may be taken with or without food. However, avoid taking amprenavir with high-fat foods or high-fat meals. The amount of drug in amprenavir capsules is not the same as the amount in amprenavir liquid. Do not switch between amprenavir capusles and amprenavir liquid unless your doctor tells you how many amprenavir capsules or how much amprenavir liquid you should take. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amprenavir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Amprenavir is not a cure and may not decrease the number of HIV-related illnesses. Amprenavir does not prevent the spread of HIV to other people. Continue to take amprenavir even if you feel well. Do not stop taking amprenavir without talking to your doctor.

Other uses for Agenerase [MedMaster Patient Drug Information database]

Before taking atazanavir,

  • tell your doctor and pharmacist if you are allergic to atazanavir or any other medications.
  • do not take atazanavir if you are taking cisapride (Propulsid), ergot alkaloids such as dihydroergotamine (Migranal, D.H.E. 45), ergonovine (Ergotrate), ergotamine (Cafergot, Ercaf, others), or methylergonovine (Methergine); midazolam (Versed); pimozide (Orap); and triazolam (Halcion).
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking. Be sure to mention amiodarone (Cordarone); anticoagulants ('blood thinners') such as warfarin (Coumadin); antidepressants (mood elevators) such as amitriptyline (Elavil ), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nefazodone (Serzone), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antifungals such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); calcium channel blockers such as bepridil (Vascor), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), nicardipine (Cardene), nifedipine (Adalat, Procardia) and verapamil (Calan, Isoptin, Verelan); carbamazepine (Tegretol); celecoxib (Vioxx); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor), lovastatin (Mevacor), or simvastatin (Zocor); cimetidine (Tagamet); clarithromycin (Biaxin); clozapine (Olozaril); cyclobenzaprine (Flexeril); danazol (Danocrine); dexamethasone (Decadron); diclofenac (Voltaren); digoxin (Lanoxin); ethosuximide (Zarontin); famotidine (Pepcid); fluvastatin (Lescol); glipizide (Glucotrol); ibuprofen (Advil, Motrin); irbesartan (Avapro); irinotecan (Camptosar); isoniazid (INH, Nydrazid); medications for irregular heartbeat; medications that suppress the immune system such as cyclosporine (Neoral, Sandimmune), sirolimus (Rapamune), and tacrolimus (Prograf); metronidazole (Flagyl); mexiletine (Mexetil); naproxen (Aleve, Naprosyn); nizatidine (Axid); oral contraceptives (birth control pills); other medications for HIV or AIDS such as delavirdine (Rescriptor), efavirenz (Sustiva), indinavir (Crixivan), nelfinavir (Viracept); ritonavir (Norvir), saquinavir (Fortovase, Invirase) and tenofovir (Viread); phenobarbital (Luminal, Solfoton); phenytoin (Dilantin); piroxicam (Feldene); proton-pump inhibitors used for indigestion, heartburn, or ulcers such as esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), and rabeprazole (Aciphex); quinidine (Quinidex); ranitidine (Zantac); rifabutin (Mycobutin); rifampin (Rimactane, Rifadin, others); tacrine (Cognex); theophylline (Theo-Dur, others); tolbutamide (Orinase); torsemide (Demadex); troleandomycin (TAO); and zafirlukast (Accolate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • If you are taking antacids, didanosine chewable or dispersible buffered tablets (Videx), or any other buffered medication such as buffered aspirin (Bufferin), take atazanavir 2 hours before or 1 hour after you take these medications. Ask your doctor or pharmacist if you are not sure if any of the medications you are taking are buffered.
  • tell your doctor what herbal products you are taking, especially St. John's wort.
  • tell your doctor if you are taking medications for erectile dysfunction such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra). You should know that atazanavir may increase the chance that you will experience serious side effects from these medications. If you are taking any of these medications and you experience dizziness, fainting, upset stomach, changes in vision, or a painful erection that lasts for several hours, call your doctor right away.
  • tell your doctor if you have or have ever had an irregular heartbeat, diabetes, hemophilia (a condition in which the blood does not clot normally), liver disease such as hepatitis (a viral infection of the liver), or kidney, or heart disease.
  • tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking atazanavir, call your doctor. You should not breastfeed if you are infected with HIV or are taking atazanavir.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking atazanavir.
  • you should know that your body fat may increase or move to different areas of your body such as your breasts, waist, and upper back.


What side effects can Agenerase cause? [MedMaster Patient Drug Information database]

Amprenavir may cause hyperglycemia (high blood sugar). Call your doctor immediately if you have any of the following symptoms:
  • extreme thirst
  • frequent urination
  • extreme hunger
  • weakness
  • blurred vision

If high blood sugar is not treated, a serious, life-threatening condition called diabetic ketoacidosis could develop. Call your doctor immediately if you have any of the these symptoms:
  • dry mouth
  • upset stomach and vomiting
  • shortness of breath
  • breath that smells fruity
  • decreased consciousness

Amprenavir may cause other side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • upset stomach
  • vomiting
  • diarrhea or loose stools
  • stomach pain
  • change in taste
  • tingling sensation around your mouth

If you experience any of the following symptoms, call your doctor immediately:
  • rash
  • seizures (if you are taking the liquid)
  • confusion (if you are taking the liquid)
  • rapid heart rate (if you are taking the liquid)

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at
http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].



Brand names for Agenerase [MedMaster Patient Drug Information database]

  • Agenerase®


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